Krogan Lab
We use systems biology approaches to connect sequence to mechanism and structure, bridging clinical to basic research.

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The Krogan lab is based at the Quantitative Biosciences Institute (QBI) at UCSF and the Gladstone Institute of Data Science and Biosciences (GIDB).

Our research focuses on fundamental biological mechanisms, because cures to many diseases have been revealed by unexpected discoveries in the basic sciences. Complementing technologies that allow the unbiased study of protein-protein interactions, protein modifications, and the effects of combinatorial gene deletions help us inform targeted mechanistic and structural studies, further paving the way to drug development. We strongly believe that impactful research is accomplished when diverse groups of scientists work together, and therefore we are working in close collaboration with experts from different disciplines on all of our projects.