Cell Mapping
Cell Maps comprehensively depict the genetic and physical interactions among genes and their products (primarily proteins) in any cell, and help us understand how these interactions are impacted by alterations in the genes.

One of the new approaches developed in collaboration with experts across the UC system and beyond is reflected in a variety of ‘Cell Mapping Initiatives’, which we apply to many biological or biomedical problems, including infectious diseases (HPMI), cancer (CCMI) as well as neurological and psychiatric disorders (PCMI). In these projects, we create cell maps by comprehensively identifying the protein complexes that work together to ensure healthy cell physiology. Using this information, we study how disease mutations or infections adversely change these protein networks and, ultimately, how drugs or other treatments can overcome these changes.